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Table 6 Regression model to assess the factors that influence the total cost per patient per year

From: Characterization of the patterns of care, access, and direct cost of systemic lupus erythematosus in Brazil: findings from the Macunaíma study

 

Coefficient

SE

z

P>|z|

[0.025

0.975]

Exponential of the coefficient

Medications: Methotrexate

-0.312

0.138

-2.261

0.024

-0.582

-0.041

0.732

Medications: Mychophenolate

1.299

0.112

11.579

0.000

1.079

1.518

3.664

Exams: Liver function tests

0.275

0.110

2.491

0.013

0.059

0.491

1.317

Lupus classification: Arthritis

-0.524

0.111

-4.733

0.000

-0.741

-0.307

0.592

Accrual damage: SDI

0.163

0.052

3.119

0.002

0.061

0.266

1.177

Exams: Erythrocyte sedimentation rate (ESR) or C-reactive protein

-0.964

0.219

-4.400

0.000

-1.394

-0.535

0.381

Medications: Antihypertensive or antidigitalis or antianginal medicines

0.623

0.131

4.769

0.000

0.367

0.879

1.864

HRQoL: SF-12 physical component

-0.232

0.048

-4.884

0.000

-0.326

-0.139

0.793

Medical history: Hypertension

-0.246

0.125

-1.977

0.048

-0.491

-0.002

0.782

Schooling (years)

0.154

0.048

3.189

0.001

0.059

0.248

1.166

BECC (Criterion 2)

0.350

0.096

3.628

0.000

0.161

0.538

1.418

Medical appointment: Nursing

0.381

0.172

2.207

0.027

0.043

0.719

1.463

Exams: Transthoracic echocardiogram or transesophageal echocardiogram

0.286

0.124

2.304

0.021

0.043

0.529

1.331

Exams: Urea or creatinine test

0.849

0.260

3.270

0.001

0.340

1.358

2.337

Exams: Echo Doppler carotid arteries or subclavian or lower members

0.69

0.195

3.425

0.001

0.286

1.052

1.952

Lupus classification: Hematological manifestations

0.264

0.096

2.753

0.006

0.076

0.451

1.302

Time between initial symptoms and initial treatment (months)

0.181

0.049

3.728

0.000

0.086

0.277

1.199

Time from symptom onset to first consultation with rheumatologist (years)

-0.140

0.047

-2.986

0.003

-0.232

-0.048

0.869

SDI: Cataract

-0.290

0.137

-2.115

0.034

-0.558

-0.021

0.748

Caregiver cost

0.530

0.174

3.042

0.002

0.188

0.871

1.699

SLEDAI score: 2–6

-0.280

0.111

-2.518

0.012

-0.497

-0.062

0.756

Exams: Myocardial injury biomarker

0.350

0.152

2.307

0.021

0.053

0.646

1.418

Intercept*

7.032

0.220

32.034

0.000

6.602

7.462

1132.519

  1. *The constant term in regression analysis and part of model building. SLEDAI 2–6: compared to the other SLEDAI categories, a score of 2–6 reduces the cost by US$1,699. Having a cataract has a lower cost compared to someone who does not have a cataract. SF-12: an increase of 1 unit in the SF-12 score reduces the average total cost by 21%. BECC, Brazilian Economic Classification Criteria; HRQoL, health-related quality of life; SDI, Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index; SE, standard error; SF-12, 12-Item Short Form Survey; SLEDAI, Systemic Lupus Erythematosus Disease Activity Index
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Advances in Rheumatology

ISSN: 2523-3106